Names & Taxonomy
- Uniprot ID:
- Q5JVS0
- Entry Name:
- HABP4_HUMAN
- Status:
- reviewed
- Protein Names:
- Intracellular hyaluronan-binding protein 4 (IHABP-4) (IHABP4) (Ki-1/57 intracellular antigen)
- Gene Names:
- HABP4
- Gene Names Primary:
- HABP4
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 413
- Sequence:
- MKGALGSPVAAAGAAMQESFGCVVANRFHQLLDDESDPFDILREAERRRQQQLQRKRRDEAAAAAGAGPRGGRSPAGASGHRAGAGGRRESQKERKSLPAPVAQRPDSPGGGLQAPGQKRTPRRGEQQGWNDSRGPEGMLERAERRSYREYRPYETERQADFTAEKFPDEKPGDRFDRDRPLRGRGGPRGGMRGRGRGGPGNRVFDAFDQRGKREFERYGGNDKIAVRTEDNMGGCGVRTWGSGKDTSDVEPTAPMEEPTVVEESQGTPEEESPAKVPELEVEEETQVQEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSKYRDDMVKDDYEDDSHVFRKPANDITSQLEINFGNLPRPGRGARGGTRGGRGRIRRAENYGPRAEVVMQDVAPNPDDPEDFPALS
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm. Nucleus. Note=Transported into the nuclear compartment in activated leukocytes.
Function
- Function:
- May be involved in nuclear functions such as the remodeling of chromatin and the regulation of transcription.
- Cross Reference Drug Bank:
- DB08818
- Gene Ontology Go:
- cytoplasm
cytosol
extracellular region
nucleoplasm
nucleus
sarcomere
blood coagulation
cellular response to mechanical stimulus
negative regulation of DNA binding
platelet activation
platelet degranulation
regulation of transcription, DNA-templated
transcription, DNA-templated - Gene Ontology Biological Process:
- blood coagulation
cellular response to mechanical stimulus
negative regulation of DNA binding
platelet activation
platelet degranulation
regulation of transcription, DNA-templated
transcription, DNA-templated - Gene Ontology Cellular Component:
- cytoplasm
cytosol
extracellular region
nucleoplasm
nucleus
sarcomere - Keywords:
- Alternative splicing
Coiled coil
Complete proteome
Cytoplasm
Nucleus
Phosphoprotein
Reference proteome
Transcription
Transcription regulation - Interacts With:
- Q99873; Q13242; O60506