Names & Taxonomy

Uniprot ID:
Q5DT03
Entry Name:
Q5DT03_HUMAN
Status:
unreviewed
Protein Names:
UDP-glucuronosyltransferase (EC 2.4.1.17)
Gene Names:
UGT1A1 BILIQTL1 hCG_2039726
Gene Names Orf:
hCG_2039726
Gene Names Primary:
UGT1A1
Organism:
Homo sapiens (Human)

Structure

Length:
533
Sequence:
MAVESQGGRPLVLGLLLCVLGPVVSHAGKILLIPVDGSHWLSMLGAIQQLQQRGHEIVVLAPDASLYIRDGAFYTLKTYPVPFQREDVKESFVSLGHNVFENDSFLQRVIKTYKKIKKDSAMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLEFEATQCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQREVTVQDLLSSASVWLFRSDFVKDYPRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH

Subcellular location

Subcellular Location:
Membrane

Function

Catalytic Activity:
UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.
Gene Ontology Go:
cytochrome complex
endoplasmic reticulum chaperone complex
integral component of plasma membrane
glucuronosyltransferase activity
acute-phase response
biphenyl catabolic process
cellular response to ethanol
cellular response to glucocorticoid stimulus
liver development
organ regeneration
response to drug
response to lipopolysaccharide
response to nutrient
response to starvation
Gene Ontology Biological Process:
acute-phase response
biphenyl catabolic process
cellular response to ethanol
cellular response to glucocorticoid stimulus
liver development
organ regeneration
response to drug
response to lipopolysaccharide
response to nutrient
response to starvation
Gene Ontology Molecular Function:
glucuronosyltransferase activity
Gene Ontology Cellular Component:
cytochrome complex
endoplasmic reticulum chaperone complex
integral component of plasma membrane
Keywords:
Glycosyltransferase
Membrane
Signal
Transferase
Transmembrane
Transmembrane helix

Publication

PubMed ID:
11181995 14672974 15489334