Names & Taxonomy
- Uniprot ID:
- Q4VNC1
- Entry Name:
- AT134_HUMAN
- Status:
- reviewed
- Protein Names:
- Probable cation-transporting ATPase 13A4 (EC 3.6.3.-) (P5-ATPase isoform 4)
- Gene Names:
- ATP13A4 UNQ3052/PRO9871
- Gene Names Orf:
- UNQ3052/PRO9871
- Gene Names Primary:
- ATP13A4
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 1196
- Sequence:
- MGHFEKGQHALLNEGEENEMEIFGYRTQGCRKSLCLAGSIFSFGILPLVFYWRPAWHVWAHCVPCSLQEADTVLLRTTDEFQIYSWKKVIWIYLSALNSAFGLTPDHPLMTDEEYIINRAIRKPDLKVRCIKVQKIRYVWNYLEGQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLICGPNTIDVEVTPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLILTGNKVLMPCDAVLIEGSCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTVIVQEMGGDRLAFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIALAYKKLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMSPTAPEKMESNSTFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILFADIPELYRRLDLLCTPVLWRASIVIMLSLNFIVSLVAEEAVIENRALWMMIKRCFGYQSKSQYRIWQRDLANDPSWPPLNQTSHSDMPECGRGVSYSNPVFESNEEQL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane
Function
- Catalytic Activity:
- ATP + H(2)O = ADP + phosphate.
- Active Site:
- ACT_SITE 486 486 4-aspartylphosphate intermediate.
- Gene Ontology Go:
- integral component of plasma membrane
intracellular membrane-bounded organelle
plasma membrane
ATP binding
cation-transporting ATPase activity
metal ion binding
cation transmembrane transport
cellular calcium ion homeostasis
ion transmembrane transport
transmembrane transport - Gene Ontology Biological Process:
- cation transmembrane transport
cellular calcium ion homeostasis
ion transmembrane transport
transmembrane transport - Gene Ontology Molecular Function:
- ATP binding
cation-transporting ATPase activity
metal ion binding - Gene Ontology Cellular Component:
- integral component of plasma membrane
intracellular membrane-bounded organelle
plasma membrane - Keywords:
- ATP-binding
Alternative splicing
Chromosomal rearrangement
Complete proteome
Hydrolase
Magnesium
Membrane
Metal-binding
Nucleotide-binding
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix